Bocavirus is one of the viral infection agents seen especially in childhood that mostly affects the respiratory tract. With the development of laboratory diagnostic methods in recent years, this virus, more frequently identified, can present with findings similar to upper respiratory tract infections. Although in most cases it presents a mild and self-limiting condition, some children may require closer monitoring.
Bocavirus (HBoV) is a viral virus that belongs to the Parvoviridae family. First identified in 2005, this virus is considered one of the most common causes of respiratory infections in children worldwide.
Bocavirus can cause an infection on its own, but is often seen as a co-infection with other viruses such as RSV (Respiratory Syncytial Virus) or Influenza. While it is most commonly detected in children aged 6 months to 3 years, it may present more prominently in infants whose immune systems have not yet fully developed.
Bocavirus is contagious and its incidence can increase during seasonal transitions, especially in winter and spring. The transmission routes are similar to other viral respiratory diseases:
Droplet Transmission: The primary mode of transmission is inhalation of droplets spread into the air when an infected person coughs, sneezes, or talks.
Close Contact: Shaking hands, hugging, or kissing infected individuals can facilitate the virus transmission.
Shared Items: The virus can remain viable on inanimate surfaces for a time. Transmission can occur through toys in daycares, door handles, or shared towels.
Contaminated Hands: Touching a surface contaminated with the virus and then touching the mouth, nose, or eyes can pave the way for infection.
Bocavirus infection starts as a mild cold but the severity of the condition may change when it descends into the lower respiratory tract. Common symptoms of bocavirus include:
High or Moderate Fever: This is the first sign that the body is fighting off the virus.
Runny and Blocked Nose: This is a classic upper respiratory infection finding.
Cough: The initially dry cough may become productive in the following days.
Wheezing: Wheezing similar to a whistling sound may be heard as the bronchi are affected in young children.
Sore Throat and Difficulty Swallowing: Inflammation in the throat can lead to loss of appetite.
Weakness and Irritability: Tiredness and an ache in the body can be observed in children, making them more inclined to sleep.
Digestive System Complaints: In some cases, respiratory symptoms may be accompanied by diarrhea, vomiting, and abdominal pain .
In healthy individuals, bocavirus usually presents as a self-limiting disease. However, the condition may be more severe in certain groups:
Premature Infants: Babies whose lung development is not yet complete.
Those with Chronic Lung Diseases: Children with disorders such as asthma or bronchopulmonary dysplasia.
Congenital Heart Diseases: Individuals with weak heart and circulatory systems.
Immunocompromised Individuals: Those receiving chemotherapy or with immunodeficiency.
Young Children Attending Daycare and School: The disease can be more persistent due to the constant exposure to viral load.
Differentiating bocavirus from other viral infections is difficult through clinical examination. Laboratory tests may be necessary for a definitive diagnosis.
PCR Test: This is a reliable method for diagnosing bocavirus. A swab sample collected from the nose and throat is screened for the virus's genetic material.
Respiratory Panel: Extended Respiratory Panel tests can screen for 15-20 different viruses including bocavirus from a single swab at the same time.
In children with a good overall condition who can be cared for at home, testing may not be deemed necessary. However, in cases where the fever does not subside, respiratory distress begins, or there is an underlying chronic illness, it is crucial to conduct tests for differential diagnosis.
There is no specific antiviral medication developed for bocavirus. The main goal of treatment is to alleviate the patient's symptoms and support the body in overcoming the virus.
Fluid Support: Replacing the fluid lost due to fever and respiratory tract, and softening of the phlegm are important. Consumption of plenty of water, breast milk, or soup should be encouraged.
Fever Control: Antipyretics may be used upon a physician's recommendation.
Nasal Hygiene: Keeping the nasal passages open with saline can help the child breathe and eat more comfortably.
Rest: Rest is necessary for the body to focus its energy on recovery.
The specialties that children and adults with bocavirus symptoms should consult may vary. To ensure accurate diagnosis and timely intervention, appointments should be made with the following departments:
Pediatrics: Since bocavirus is most commonly seen in infants and children, pediatricians are the first point of contact. A specialist physician, if necessary after physical examination, may request a respiratory panel test to clarify the diagnosis.
Pediatric Infectious Diseases: If the disease recurs, if there is a risk related to the child's immune system, or if the condition progresses severely like pneumonia, it is advisable to consult with specialists in this area.
Otolaryngology (ENT): In cases accompanied by severe sore throat, suspicion of middle ear infection, or adenoid problems, evaluation by an ENT specialist may be necessary.
Infectious Diseases and Clinical Microbiology: Although bocavirus rarely progresses severely in adults and the elderly, adult patients can consult an infectious disease specialist if needed.
The course of the disease varies according to the individual's immune system. Typically, symptoms start diminishing within 7 to 10 days. However, complaints such as cough and weakness may take 2-3 weeks to completely resolve.
During home care:
Humidity levels in the room should be maintained.
Exposure to cigarette smoke should be avoided.
A diet of small, frequent meals should be adopted.
There is currently no specific vaccine developed for bocavirus. Therefore, general hygiene measures and immune-supportive precautions should be focused on to protect against the virus, especially in winter and spring.
Hand Hygiene: The most effective way to prevent the virus is to wash hands with soap and water for at least 20 seconds. Children should be taught to wash their hands before eating, after coming from outside, and after using the bathroom.
Avoiding Contact: People showing signs of illness should be avoided as much as possible. Time spent in crowded and enclosed spaces should be limited.
Surface Disinfection: Regular disinfection should be carried out on doorknobs, light switches, and toys used in common by children. The virus can remain viable on hard surfaces for a long time.
Keeping Hands Away from the Face: The virus enters the body through the mouth, nose, and eyes. Children should be educated about not touching their faces with their hands.
Ventilation: Environments such as homes, classrooms, and daycares should be frequently ventilated during the day to reduce the viral load indoors.
Healthy Eating and Sleep: The immune system is the greatest ally in fighting the virus. Seasonal vegetable-fruit consumption and regular sleep schedule boost children's resistance.
Preventing Sharing of Personal Items: During illness periods, care should be taken to avoid sharing items such as cups, towels, cutlery, and pillows.
Bocavirus typically resolves with symptom relief within 5 to 10 days. However, the cough and runny nose may last longer in some children.
The bocavirus test is done using the PCR method when deemed necessary. A swab sample collected from the nose and throat is examined in a laboratory setting to investigate the presence of the virus.
Immunity may develop after bocavirus infection, but children may experience similar symptoms again due to different viral infections.
In some cases, bocavirus can affect the lower respiratory tract leading to symptoms like wheezing. This situation should be closely monitored, especially in young infants.