Vitamin B12 is vital for many processes such as nervous system health and red blood cell production. However, due to dietary habits, gastrointestinal disorders, absorption issues, and the use of certain medications, B12 levels may decrease. B12 deficiency may initially go unnoticed; however, over time it can lead to neurological, psychiatric, and hematological symptoms that significantly affect a person's quality of life.

What is Vitamin B12?

Cobalamin, or Vitamin B12, is a vitamin found primarily in animal foods such as dairy products, eggs, fish, and red meat, and is not produced by the body. It is necessary for the formation of red blood cells, nervous system functions, and DNA synthesis. It is consumed as protein-bound in foods and becomes absorbable through the action of stomach acid and enzymes.

What Does Vitamin B12 Do?

Vitamin B12 can help prevent anemia by supporting the production of red blood cells and plays an important role in the formation of the myelin sheath necessary for the healthy functioning of the nervous system. It is also a fundamental vitamin for cell regeneration and DNA synthesis. Since it supports energy metabolism, it has a determining effect on fatigue, weakness, and mental performance.

What are the Benefits of Vitamin B12?

Vitamin B12 plays an active role in many essential biological processes such as protecting nerve cells and energy production. Adequate intake of B12 can support both the maintenance of nervous system health and the healthy regeneration of cells in the body. The main benefits of Vitamin B12 include:

  • It may help the nervous system function regularly and healthily.

  • Supports cognitive performance; B12 deficiency is associated with forgetfulness and mental slowing.

  • Can increase the body's energy production by strengthening energy metabolism.

  • Works with folate to support healthy red blood cell production and can help prevent anemia.

  • Supports efficient metabolism by facilitating the conversion of carbohydrates into energy.

  • Helps maintain balanced homocysteine levels in the blood, which can positively impact heart and vascular health.

What is B12 Deficiency?

B12 deficiency is a condition that arises when the body cannot receive or absorb enough vitamin B12, which is necessary for the nervous system, blood cells, and energy metabolism. 

Since the absorption process occurs in the stomach and intestines, nutritional deficiency, decreased stomach acid, intestinal diseases, or the use of certain medications can lead to deficiency. Prolonged B12 deficiency can cause health issues such as fatigue, forgetfulness, nervous system disorders, and anemia.

What are the Symptoms of B12 Deficiency?

B12 deficiency can lead to numerous physical and psychological symptoms since it affects the nervous system and the production of blood cells. As the deficiency progresses, the symptoms may become more pronounced. The most common symptoms of B12 deficiency include:

  • Constant fatigue and weakness

  • Dizziness, shortness of breath, and palpitations

  • Numbness, tingling in the hands and feet

  • Difficulty concentrating, forgetfulness, and mental confusion

  • Mood changes, restlessness, and feeling depressed

  • Pale skin appearance and burning of the tongue

  • Muscle weakness and balance issues

Assessing symptoms early is crucial as advancing B12 deficiency can lead to permanent effects on the nervous system.

Which Foods Provide Vitamin B12?

Vitamin B12 is primarily found in animal foods, and regular intake is important for the health of the nervous system and blood cells. The following foods are either rich in B12 or support daily intake:

  • Protein-rich meat products such as red meat, turkey, and chicken

  • Seafood such as salmon, sardines, tuna, shrimp, and mussels

  • Offal with high B12 content such as liver, kidney, and spleen

  • Dairy products such as milk, yogurt, and cheese

  • Eggs 

  • B12-fortified plant products 

Who is Prone to Vitamin B12 Deficiency?

Vitamin B12 deficiency can occur in different age groups and populations due to both insufficient intake and absorption problems. It is more common in people who do not consume animal foods and those with issues related to gastrointestinal health. 

  • Vegans and vegetarians

  • Elderly individuals 

  • Individuals who have undergone stomach or bowel surgery

  • Those on long-term use of stomach-protective medications

  • Those with bowel diseases causing absorption issues 

  • Pregnant and breastfeeding mothers 

  • Individuals with chronic alcohol use

  • People with irregular or monotonous diets

How is Vitamin B12 Deficiency Treated?

An important part of the treatment involves evaluating dietary habits. In individuals with insufficient consumption of animal proteins, red meat, fish, eggs, and dairy products can be added to the diet plan. For those on vegan diets, B12-fortified products and regular supplementation are recommended.

In some patients, the cause of the deficiency may be insufficient stomach acid, stomach surgery, or intestinal diseases. In such cases, along with medication, the underlying problem should also be managed. During the treatment process, B12 levels are regularly monitored under medical supervision, and maintenance therapy may be planned if necessary.

Frequently Asked Questions

Does Vitamin B12 Deficiency Cause Psychological Symptoms?

Yes. Psychological symptoms of B12 deficiency include depressive mood, increased anxiety, restlessness, focus issues, and memory problems. These symptoms can be common as the support for the nervous system decreases.

What Should Those with B12 Deficiency Avoid Eating?

Excessive consumption of tea and coffee, alcohol use, and a high-fiber diet that hinders absorption can reduce B12 intake. Diets lacking supplementation in vegans can also exacerbate the deficiency.

What Does B12 Deficiency Lead To?

If untreated, B12 deficiency can lead to anemia, nerve damage, balance problems, forgetfulness, blurred vision, and permanent neurological issues. Long-term deficiency increases the risk of cognitive decline in older age.

How is Vitamin B12 Deficiency Diagnosed?

Symptoms and blood tests are evaluated together. Serum B12 level, methylmalonic acid (MMA), and homocysteine levels can provide information about deficiency.

Creation Date : 08.12.2025
Update Date : 11.12.2025
Author : Yeliz YİĞİT
Communication : +905303120237
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