Diabetes is a chronic metabolic disease that can present with various types and clinical pictures. In some individuals, despite treatments, blood sugar levels may fluctuate unpredictably and abruptly during the day. This situation may point to a specific form of diabetes known in the literature as brittle diabetes. Brittle diabetes is a condition where blood sugar control is difficult and is characterized by frequent episodes of hypoglycemia and hyperglycemia.

What is Brittle Diabetes?

Brittle diabetes is a form of diabetes characterized by sudden spikes and drops in blood sugar levels within short periods. It is most commonly seen in individuals with Type 1 diabetes, although patients with Type 2 diabetes may experience similar control difficulties under certain conditions.

In the case of brittle diabetes, maintaining glycemic balance may be challenging despite standard insulin therapies. Daily life activities, dietary habits, stress levels, and hormonal changes can have significant effects on blood sugar.

What Causes Brittle Diabetes?

There is no single cause of brittle diabetes. It generally develops due to the convergence of multiple factors.

  • Irregularities in insulin absorption: Tissue changes at injection sites can affect insulin absorption.

  • Hormonal fluctuations: Conditions like thyroid diseases and adrenal hormone disorders can make it difficult to control blood sugar levels.

  • Psychological and emotional factors: Stress, anxiety, and depression can increase glycemic fluctuations.

  • Nutritional irregularities: Skipping meals, imbalanced carbohydrate intake, or sudden dietary changes can affect blood sugar.

  • Accompanying diseases: Infections, gastrointestinal problems, or absorption disorders can also play a role.

Each of these factors can make blood sugar levels unpredictable.

What are the Symptoms of Brittle Diabetes?

The symptoms of brittle diabetes often develop rapidly and exhibit a fluctuating pattern. 

Commonly encountered symptoms of brittle diabetes include:

  • Sudden hypoglycemic attacks: Unexpected drops in blood sugar may lead to sweating, trembling, palpitations, dizziness, blurred vision, and confusion.

  • Sudden hyperglycemic elevations: Rapid increases in blood sugar can cause dry mouth, frequent urination, fatigue, and intense thirst.

  • Frequent fluctuations in blood sugar during the day: Significant differences between measurements can make glycemic control more difficult.

  • Fatigue and low energy: Continuously changing blood sugar levels can make a person feel tired and exhausted throughout the day.

  • Difficulty in concentration: Sudden drops can lead to distractions and focus issues.

  • Frequent need for emergency intervention: The necessity to seek emergency medical support may increase due to hypoglycemic and hyperglycemic attacks.

Symptoms may not appear with the same severity in every individual. However, frequent and uncontrolled blood sugar fluctuations are considered important clinical findings that need careful evaluation in terms of brittle diabetes.

How is Brittle Diabetes Diagnosed?

The diagnosis of brittle diabetes is not based on a single blood sugar measurement. The diagnosis process requires the evaluation of the patient's clinical history, daily blood sugar fluctuations, and responses to treatments together. The goal is to determine the causes of sudden and unpredictable changes in blood sugar levels.

  • Detailed assessment of the patient's history: Frequent hypoglycemic and hyperglycemic attacks, emergency visits, hospital admission history, and daily life control difficulties are examined.

  • Daily blood sugar monitoring records: Home measurements can provide important information about the frequency and severity of daily fluctuations.

  • Analysis of HbA1c and glycemic variability: The average blood sugar level indicated by the HbA1c value is assessed along with the variability between measurements.

  • Continuous glucose monitoring (CGM) systems: These provide detailed information about the course of blood sugar throughout the day, helping to detect sudden drops and spikes.

  • Investigation of accompanying conditions: Factors such as hormonal disorders, infections, absorption problems, or medications used are evaluated.

How is Brittle Diabetes Treated?

There is no single treatment approach for brittle diabetes. The main goal is to reduce blood sugar fluctuations and create an individualized management plan.

  • Personalized insulin therapy

  • Insulin pumps and continuous glucose monitoring systems

  • Personalized dietary planning

  • Regular medical follow-up and education

The treatment plan is determined by a specialist physician, taking into account the patient's lifestyle, daily habits, and accompanying health issues.

Frequently Asked Questions

Is brittle diabetes permanent?

Brittle diabetes may be limited to a temporary period in some individuals, while others may require long-term monitoring. Identifying underlying causes can influence the course of the condition.

Is brittle diabetes dangerous?

It is a condition that needs careful monitoring due to frequent hypoglycemic and hyperglycemic episodes. Risks can be minimized with appropriate monitoring and treatment.

Who is affected by brittle diabetes?

It is most commonly seen in individuals with Type 1 diabetes. Assessment may be necessary for patients experiencing difficulties in blood sugar control.

What is the difference between brittle diabetes and regular diabetes?

In brittle diabetes, blood sugar fluctuations are more sudden and unpredictable. This condition may require a different approach from standard diabetes management.

Creation Date : 26.01.2026
Update Date : 03.02.2026
Author : Yeliz YİĞİT
Communication : +905303120237
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